In one study of 6,000 participants, 10% of those who took omeprazole for three years experienced memory loss. Another study found that 33% of patients taking the medication for more than 4.5 years reported cognitive problems. This may be due to decreased absorption of vitamin B12, which is essential for nerve cell function.
Omeprazole is often used without a prescription, but it is important to consult a doctor before starting long-term treatment. Treatment for benign prostatic hyperplasia (BPH) should generally be limited to periods of two to three months, depending on individual needs and dietary adjustments.
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Anticholinergics are used to treat various conditions, including Parkinson’s disease and urinary tract disorders. They work by blocking acetylcholine, a neurotransmitter essential for memory and learning. Studies suggest they may increase the risk of dementia. For example, a University of Washington study followed more than 3,500 adults for 10 years and found that those who regularly used anticholinergics had a 54% increased risk of developing dementia.
Common anticholinergics associated with cognitive decline include meclizine, scopolamine, piperidine, oxybutynin, and diphenhydramine. However, others, such as glycopyrrhenium and tiotropium, have not shown these effects. Patients and physicians should carefully weigh the risks and benefits of these medications.
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